PERSONAL DATA
Name: I-Shin Shiah
Date of Birth: August, 25, 1964
Marital Status: Married to Jasmine Hsiu-Ling, Huang, 1990
Children: Charlene born 1992; Charles born 1997
Address: 2255 Wesbrook Mall, Vancouver, BC, Canada, V6T 2A1
EDUCATION
1995-1999 Doctor of Philosophy, Neuroscience Graduate Program, Faculty of Graduate Study, University of British Columbia, Vancouver, BC, Canada
1982-1989 Doctor of Medicine, National Defense Medical Center, Taipei, Taiwan
1988-1989 Internship,Veterans General Hospital, Taipei
1987-1988 Clerkship, Tri-Service General Hospital, Taipei
1979-1982 Taipei Municipal Chien-Kuo Senior High School
LICENSES, CERTIFICATION, QUALIFICATION
1998 Ph.D. Candidate comprehenisve examinaiton, The Depratment of Neuroscience, Unviersity of British Columbia
1995-Date Practice License in Psychiatry, College of Physicians and Surgeons, British Columbia, Canada
1995 National Board of Psychiatry, Taiwan
1994 Graduate Record Examinations (GRE)
1993 Tests of English as a Foreign Language (TOEFL) : 610
1991 National Board of Professional and Technician in Medicine, Taiwan
1990 Certification of Educational Commission for Foreign Medical Graduates (ECFMG), USA
1989 Certification of Flight Surgeon, Air Force, Taiwan
1989 Practice License of Physician, Taiwan
ACADEMIC AWARDS AND DISTINCTIONS
1999 Young Investigator's Award (First Prize), Tri-Service General Hospital
1999 Travel Bursary for the Best Abstracts, Canadian College of Neuropsychopharmacology (CCNP)
1999 Graduate Student Travel Funding, Faculty of Medicine, University of British Columbia, Canada
1998 Dr. Tsung-Yi Lin Award for the Best Clinical Research Paper at the 13th Annual Departmental Research Day, Department of Psychiatry, UBC, Vancouver, Canada
1995 National Loyality and Diligence Medal, Taiwan
1995 Merit award for best teaching, Clinical Faculty, Tri-Service General Hospital
1994 3rd Price for best teaching, Clinical Faculty, Tri-Service General Hospital
1994 Governmental Fellowship for PH.D. studying (1995-2000), Taiwan
1989 Air Force Aviation Medal, Taiwan
1989 3rd Price for excellence, Flight Surgeon School, Air Force, Taiwan
1989 Dr. Tsong-Ming Duh Scholarship, Formosa Medical Association, Taiwan
1989 National Scholarship Medal, Taiwan
1989 Loyal Medal, National Defense Medical Center, Taiwan
1989 1st Price for excellence, Medical graduate, National Defense Medical Center
1988 1st Price for excellence, Intership, Veterans General Hospital, Taipei
1988 Merit Award for excellence, Internship, Veterans General Hospital, Taipei
1988 2nd Price for excellence, Clerkship, Tri-Service General Hospital
1985 Scholarship for outstanding efforts, National Defense Medical Center
1984 Scholarship for outstanding efforts, National Defense Medical Center
RESENDENCY AND ACADEMIC EXPERIENCE
1996-Date Clinical Fellow, Department of Psychiatry, Vancouver Hospital and Health Sciences Center, B.C., Canada
1991-Date Teaching Faculty, National Defense Medical Center, Taipei, Taiwan
1995-Date Attending Psychiatrist, Department of Psychiatry, Tri-Service General Hospital, Taipei, Taiwan
1994-1995 Chief Resident, Department of Psychiatry, Tri-Service General Hospital, Taipei, Taiwan
1993 Resident (child and adolescence psychiatry, and coultation-liaison psychiatry training), Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan
1993 Resident (clinical neurology training), Department of Neurology, Tri-Service General Hosptial, Taipei, Taiwan
1992-1993 Resident (community psychiatry training), Department of Psychiatry, Military 818 Hospital, Taipei, Taiwan
1991-1994 Resident, Department of Psychiatry, Tri-Service General Hospital, Taipei, Taiwan
1990-1991 Resident, Department of Internal Medicine, Military 813 Hospital, Hsinchu, Taiwan (military service)
1989-1990 Flight Surgeon, Hsinchu Air Force Base, Taiwan (military service)
MEMBERSHIPS
1989-Date Formosa Medical Association, ROC
1989-Date Aerospace Medical Association, ROC
1989-1996 Aerospace Medical Association, USA
1991-Date Taipei Medical Association, ROC
1991-Date The Society of Psychiatry, (Taiwan), ROC
1991-Date The Society of Geriatry, ROC
1992-Date Chinese Medical Association, (Taiwan), ROC
1993-1996 The Association of Military Surgeons of USA
1994-Date Mental Health Association in Taiwan, ROC
1998-Date International Society of Psychoneuroendocrinology (ISPNE)
1999-Date New York Academy Sciences
1999-Date Society of Biological Psychiatry
( Refereed Papers: SCI = 19 , Non-SCI = 2 ; Non-Refereed Papers = 13 ; Total = 34 )
(Conference Papers: International = 29 , National = 15 , Total = 44 )
(Books = 2 )
REFEREED PAPERS (1996-Present, Total=21) For abstract, select title:
In Press
1. Lam RW, Bowering TA, Tam EM, Grewal A, Yatham LN, Shiah IS, Zis AP. Effects of rapid tryptophan depletion in patients with seasonal affective disorder in natural summer remission. Psychological Medicine 1999 (in press).
2. Shiah IS, Yatham LN. Serotonin in mania and in the mechanism of action of mood stabilizers: a review of clinical studies. Bipolar Disorders 1999 (in press)
3. Shiah IS, Yatham LN, Srisurapanont M, Lam RW, Tam EM, Zis AP. Does pindolol addition accelerate response to ECT in patients with major derpession ? A double blind, placebo-controlled pilot study Journal of Clinical Psychopharmacology 1999 (in press)
4. Lam RW, Tam EM, Shiah IS, Yatham LN, Zis AP. Effects of light therapy on suicidal ideation in patients with seasonal affective disorder. Journal of Clinical Psychiatry 1999 (in press)
1999
5. Shiah IS, Ko HC, Lee JF, Lu RB. Increased platelet 5-HT in patients with bipolar depression.Journal of Affective Disorders 1999; 55: 251-253.
6. Shiah IS, Yatham LN, Lam RW, Tam EM, Zis AP. Growth hormone response to baclofen in patients with mania: a pilot study. Psychopharmacology 1999; 147(3): 280-284.
7. Yatham LN, Liddle PF, Dennie J, Shiah IS, Adam MJ, Lane C, Lam RW, Ruth TJ. Decrease in Brain Serotoin 2 Receptor Binding in Patients with Major Depression Following Desipramine Treatment: A Positron Emission Tomography Study with Fluorine-18 labeled Setoperone. Archives of General Psychiatry 1999; 56(8): 705-711.
8. Yatham LN, Shiah IS, Lam RW, Tam EM, Zis AP. Hypothermic, ACTH and cortisol responses to ipsapirone in patients with mania and healthy controls. Journal of Affective Disorders 1999; 54(3): 295-301.
9. Shiah IS, Ko HC, Lee JF, Lu RB. Platelet 5-HT and plasma MHPG levels in patients with bipolar I and bipolar II depressions and normal controls. Journal of Affective Disorders 1999; 52: 101-110.
10.Shiah IS, Robertson HA, Lam RW, Yatham LN, Tam EM, Zis AP. Baclofen induced growth hormone response in patients with seasonal affective disorder: Effects of light therapy. Psychoneuroendocrinology 1999; 24: 143-153.
1998
11. Shiah IS, Ko HC, Lu RB. The lower limits of plasma dexamethasone window in Chinese depressives. Biological Psychiatry 1998; 44: 648-655.
12. Shiah IS, Yatham LN. GABA function in mood disorders: An update and critical review. Life Sciences 1998; 63(15): 1289-1303.
13. Shiah IS, Yatham LN, Lam RW, Tam EM, Zis AP. Cortisol, hypothermic, and behavioral responses to ipsapirone in patients with bipolar depression and normal controls. Neuropsychobiology 1998: 38(1): 6-12.
14. Shiah IS, Yatham LN, Lam RW, Zis AP. Divalproex sodium attenuates growth hormone to baclofen in healthy male humans. Neuropsychopharmacology 1998:18: 370-376.
15. Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of lamotrigine on 5-HT1A receptor function in healthy human males. Journal of Affective Disorders 1998: 49: 157-162.
1997
16. Shiah IS. Atypical antipsychotics and tardive dyskinesia. Taiwanese Journal of Psychiatry 1997: 11: 429-430.
17. Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of divalproex sodium on 5-HT1A receptor function in healthy male humans: Hypothermic, hormonal and behavioral responses to ipsapirone. Neuropsychopharmacology 1997: 17: 382-390.
18. Yatham LN, Zis AP, Lam RW, Tam EM, Shiah IS. Sumatriptan induced growth hormone release in patients with major depression, mania, and normal controls. Neuropsychopharmacology 1997: 17: 258-263.
19. Ko HC, Lu RB, Shiah IS, Hwang CC. Plasma free 3-methoxy- 4-hydroxyphenycol predicts response to fluoxetine. Biological Psychaitry 1997: 41: 774-781.
1996
20. Shyu WC, Lin JC, Shen CC, Hsu YD, Lee CC, Shiah IS, Tsao WL. Vascular dementia of Binswanger's type: Clinical, neuroradiological and 99mTC-HMPAO SPET study. European Journal of Nuclear Medicine 1996: 23: 1338-1344.
21. Shiah IS, Lin JC, Shen JJ, Lu RB. Wernicke's aphasia caused by intracerebral hemorrhage associated with methamphetamine inhalation: Report of a case. Chinese Psychiatry 1996: 10: 188-194.
NON-REFEREED PAPERS (in Chinese)(1992-1996, Total=13)
1996
25. Wang GT, Shiah IS, Chen HY, Shen JJ. Delirium in the elderly patients. Medical Digest 1996; 22: 338-341.
26. Chen SP, Shiah IS, Lu RB. Psychiatric emergency in the elderly. Continuing Medical Education 1996; 6: 144-151.
1995
27. Shyu WS, Shiah IS, Jiang HK. Diagnosis and treatment of anxiety in the elderly. Medical Digest 1995; 20: 230-234.
28. Fan HC, Shiah IS, Lu RB. Postpartum psychiatric disorders. Medical Digest 1995; 20: 226-229.
29. Shyu WS, Shiah IS, Jiang HK. Self mutilation. Medical Digest 1995; 20: 159-163.
30. Lin JC, Shiah IS, Lu RB. Late onset schizophrenia. Medical Digest 1995; 20: 124-126.
31. Yang YS, Shiah IS, Shen JJ, Liu WC. Rapid eye movement sleep behavior disorder. Medical Digest 1995; 20: 70-73.
32. Shiah IS, Lu RB. Biofeedback therapy in anxiety and psychosomatic disorders. Medical Digest 1995; 19: 11-14.
33. Lin JC, Shiah IS, Lu RB. Diagnosis and treatment of depression in the elderly. Continuing Medical Education 1995; 5: 55-61.
1993
34. Shiah IS, Ho SL. Sleep disorders in the elderly, part two. Continuing Medical Education 1993; 3: 402-406.
35. Shiah IS, Ho SL. Sleep disorders in the elderly, part one. Continuing Medical Education 1993; 3: 260-267.
36. Shiah IS, Jiang HK, Lu RB, Yin TH. Current understanding of drug abuse in behavior science and neurobiology. Continuing Medical Education 1993; 1: 62-71.
1992
37. Shiah IS, Hwang CC, Shen JJ, Lu RB. Atypical antipsychotic-clozapine. Continuing Medical Education 1992; 2: 755-760.
(Conference Papers: Internatioanl = 29; National= 15; Total=44)
INTERNATIONAL CONFERENCE PAPERS (1996-Present, Total=29)
1999
1. Yatham LN, Liddle PF, Shiah IS, Adam MJ, Ruth TJ, Lam RW. Brain 5-HT2 receptors in major depression: a PET study. 49th Annual Meeting, Canadian Psychiatric Association, Toronto, Ontario, Canada, September, 1999.
2. Shiah IS, Yatham LN. Pindolol accelerates the antidepressant effect of ECT in patients with major depression.. 22nd Annual Meeting, Canadian College of Neuropsychopharrmacology, Halifax, Nova Scotia, Canada, June 1999.
3. Shiah IS, Yatham LN, Lam RW, Tam EM, Zis AP. Growth hormone response to baclofen in patients with mania and healthy controls. 152nd Annual Meeting, American Psychiatric Association, Washington DC, USA, May 1999.
4. Yatham LN, Liddle PF, Shiah IS, Scaran G, Adam MJ, Lam RW, Zis AP, Ruth TJ. Age related decline in 5-HT2 receptors in depressed patients and healthy controls. 152nd Annual Meeting, American Psychiatric Association, Washington DC, USA,, May, 1999.
5. Yatham LN, Shiah IS, Srisurapanont M, Lam RW, Tam EM, Zis AP. Pindolol addition accelerates antidepressant effects of ECT. 152nd Annual Meeting, American Psychiatric Association, Washington DC, USA, May, 1999.
6. Lam RW, Tam EM, Shiah IS, Yatham LN, Zis AP. Effects of light therapy on suicidal ideation in SAD patients. 152nd Annual Meeting, American Psychiatric Association, Washington DC, USA, May, 1999.
7. Shiah IS, Yatham LN, Srisurapanont M, Lam RW, Tam EM, Zis AP. Pindolol accelerates antidepressant effects of ECT in depression. 54th Annual Meeting, Society of Biological Psychiatry, Washington DC, USA, May, 1999.
8. Leu SJ, Shiah IS, Cheu YM, Lam RW. Immune- inflammatory markers in patients with SAD: effects of light therapy. 54th Annual Meeting, Society of Biological Psychiatry, Washington DC, USA, May, 1999.
9. Yatham LN, Liddle PF, Dennie J, Shiah IS, Adam MJ, Lane CJ, Lam RW, Ruth TJ. Effects of desipramine treatment on brain 5-HT2 receptors in depression. 54th Annual Meeting, Society of Biological Psychiatry, Washington DC, USA, May, 1999.
10. Shiah IS, Yatham LN. Growth hormone response to baclofen in manic pateints and healthy controls. 14th Annual Departmental Research Day, Department of Psychiatry, UBC, Vancouver, Canada, March 1999.
11. Shiah IS, Yatham LN. Pindolol accelerates the antidepressant effect of ECT in patients with major depression. 14th Annual Departmental Research Day, Department of Psychiatry, UBC, Vancouver, Canada, March 1999.
1998
12. Yatham LN, Dennie J, Shiah IS, Lane C, Lam RW, Ruth TJ, Liddle PF. A PET study of effects of desipramine or ECT on 5-HT2 receptors in depressed patients. The 48th Annual Meeting, Canadian Psychiatric Association, Halifax, Canada, September, 1998.
13. Shiah IS, Yatham LN, Lam RW, Tam EM, Zis AP. Enhanced cortisol response to ipsapirone in mania. XXIst College of International Neuropsychopharmacology Congress, Glasgow, Scotland, UK, July 1998.
14. Yatham LN, Dennie J, Lane C, Shiah IS, Liddle PF. A PET study of effects of desipramine or ECT on 5-HT2 receptors in depressed patients. XXIst College of International Neuropsychopharmacology Congress, Glasgow, Scotland, UK, July 1998.
15. Robertson HA, Shiah IS, Lam RW, Yatham LN, Zis AP. Effects of light therapy on growth hormone response to baclofen in patients with seasonal affective disorder. 10th Annual Meeting, Society for Light Treatment and Biological Rhythms, Florida, U.S.A., May 1998.
16. Yatham LN, Shiah IS, Lam RW, Tam EM, Zis AP. Enhanced cortisol response to ipsapirone in mania. 151st Annual Meeting, American Psychiatric Association, Toronto, Canada, May 1998.
17. Shiah IS, Yatham LN, Lam RW, Tam EM, Zis AP. 5-HT1A receptor function in patients with bipolar depression.53rd Annual Meeting, Society of Biological Psychiatry, Toronto, Canada, April, 1998.
18. Shiah IS, Lu RB, Ko HC, Lee JF. Platelet 5-HT and plasma MHPG levels in bipolar I and bipolar II depressions. 53rd Annual Meeting, Society of Biological Psychiatry, Toronto, Canada, April, 1998.
19. Shiah IS, Yatham LN. Effects of divalproex on GABAB receptor function in healthy humans. 13th Annual Departmental Research Day, Department of Psychiatry, UBC, Vancouver, Canada, March 1998.
20. Shiah IS, Yatham LN. 5-HT1A receptor function in patients with bipolar mania. 13th Annual Departmental Research Day, Department of Psychiatry, UBC, Vancouver, Canada, March 1998.
1997
21. Yatham LN, Shiah IS, Lam RW, Zis AP. Divalproex attenuated baclofen-induced growth hormone response in healthy male humans. Book of Abstracts, 47th Annual Meeting, Canadian Psychiatric Association, Calgary, Canada, September, 1997, pp 94.
22. Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of divalproex sodium on 5-HT1A receptor function in healthy male humans. Proceedings, 2nd International Meeting of Bipolar Disorders, Pittsburgh, USA, June 1997, pp52.
23. Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of lamotrigine on 5-HT1A receptor function in healthy male humans. Proceedings, 2nd International Meeting of Bipolar Disorders, Pittsburgh, USA, June 1997, pp53.
24. Shiah IS, Yatham LN, Zis AP, Lam RW. Lamotrigine treatment and serotonin receptor function. New Research Abstracts, 150th Annual Meeting, American Psychiatric Association, San Diego, USA, May 1997, pp94.
25. Yatham LN, Shiah IS, Zis AP, Lam RW. Effects of divalproex on 5-HT1A receptor function in healthy male humans. New Research Abstracts, 150th Annual Meeting, American Psychiatric Association, San Diego, USA, May 1997, pp142.
26. Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of valproate on 5-HT1A receptor function in humans. Biol Psychiatry 1997; 41: 61S.
27. Shiah IS, Yatham LN, Lam RW, Zis AP. Effects of divalproex on 5-HT1A receptor function in healthy humans. UBC Department of Psychiatry Research Day, Vancouver, Canada, April 1997.
1995
28. Lu KB, Ko HC, Shiah IS, Hwang CC. Pretreatment plasma free MHPG levels as predictors of fluoxetine
response. Biol Psychiatry 1995; 37: 569.
29. Shiah IS, Ko HC, Lu RB. The lower limits of plasma dexamethasone window in Chinese depressives. Biol Psychiatry 1995; 37: 655.
NATIONAL CONFERENCE PAPERS (in Chinese)(1992-1995, Total=14)
1995
30.Chen YC, Ko HC, Shiah IS, Lu RB. The correlation between platelet 5-HT and HPA axis in depressive patients. Proceedings of the 34th anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1995.
1994
31. Shiah IS, Ko HC, Lu RB. The effect of plasma dexamethasone concentration on dexamethasone suppression test in major depressive disorder. Proceedings of the 31st anniversary of the Society of Psychiatry (Taiwan) R.O.C. 1994, pp19.
32. Lu RB, Shiah IS, Luu SU, Ko HC. Platelet serotonin and plasma MHPG concentration of major depression, anxiety disorder, and normal subjects. Proceedings of the 33rd anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1994, pp18.
33. Lu RB, Shiah IS, Hwang CC, Ko HC. Maprotiline and fluoxetine response as markers to investigate the heterogeneity of depression. Proceedings of the 33rd anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1994, pp18.
34. Ko HC, Shiah IS, Chao TC, Hsieh MH, Lu RB. Psychometric properties of adult suicidal ideation questionnaire. Proceedings of the 33rd anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1994, pp12.
35. Chen YC, Shen JJ, Shiah IS, Shyn LY, Lu RB. The development of a preschool behavior checklist. Proceedings of the 33rd anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1994, pp 60.
36. Lin JC, Shiah IS, Hwang CC, Luu SU, Jiang HK. Camptocormia and psychogenic amnesia: A case report. Proceedings of the 33rd anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1994, pp 61.
37. Lin JC, Mao WC, Shiah IS, Shen JJ, Lu RB. Cough syrup induced organic mental disorder: A case report. Proceedings of the 33rd anniversary of the Society of Psychiatry (Taiwan), R.O.C., 1994, pp 61.
1993
38. Shiah IS. Gene and Environment in mental illness (paper review). Newsletter: The Society of Psychiatry (Taiwan) R.O.C., 1993; 12: 9-10.
1992
39. Shen CC, Shiah IS, Chen WL. Cerebral perfusion imaging in complex partial seizure: Report of two cases. Proceedings of 1992 annual meeting of the Society of Nuclear Medicine, Taiwan, R.O.C. pp181-182.
40. Shiah IS, Shyu WC, Jwo ST, Shen JJ, Lu RB. Psychogenic seizure. Proceedings of the 19th annual meeting of Chinese Military Surgeons, Taiwan, R.O.C., 1992, pp27.
41. Shiah IS, Farng HK, Su CF, Lu RB. Claustrophobia, conversion disorder concomitant with Arnold-Chiari malformation and pseudomeningocele: A case report. Proceedings of the 31st anniversary of the Society of Psychiatry (Taiwan) R.O.C. 1992, pp34.
42. Shiah IS, Shyu WC, Shyu LY, Lu RB. Psychogenic seizure: Report of three cases. Proceedings of the 31st anniversary of the Society of Psychiatry (Taiwan) R.O.C. 1992, pp38-39.
43. Shiah IS, Jiang HK, Shen CC, Lu RB. Mental symptoms in complex partial seizure: Report of two cases. Proceedings of the 31st anniversary of the Society of Psychiatry (Taiwan) R.O.C. 1992, pp40-41.
44. Shiah IS, Hwang CC, Lu RB. Wernicke's aphasia in amphetamine induced intracranial hemorrhage: A case report. Proceedings of the 31st anniversary of the Society of Psychiatry (Taiwan) R.O.C. 1992, pp53.
Books:
1. Shiah IS. English Use in Medicine (ISBN: 957-666-174-9). Taipei: Ho-Chi Book Publishing Corp., 1993.
2. Shiah IS. Neuroendocrine challenge studies of serotonin and GABA function in mania and in the mechanism of action of the mood stabilizer, divalproex sodium. Ph.D. Thesis, Neuroscience Graudate Program, Faculty of Graduate Studies, The University of British Columiba, Vancouver, BC, Canada, 1999.